Actitrexx is a pioneering startup in the biotechnology sector, focusing on advanced cellular therapies. The company has developed a product called Actileucel, which is a cellular therapeutic agent designed to combat Graft-versus-Host Disease (GvHD). GvHD is a severe and often life-threatening complication that arises after stem cell transplantation, where donor immune cells attack the recipient's body tissues. This condition affects over 50% of patients undergoing stem cell transplants, with a mortality rate of around 20%.

Actileucel works by utilizing optimally activated regulatory T cells, which are natural components of our immune system. These cells help to modulate the activity of other immune cells, specifically CD4 T lymphocytes, to prevent unwanted inflammatory reactions. By suppressing the undesired activation of these lymphocytes, Actileucel aims to prevent the onset of GvHD and promote the development of a healthy immune system in patients.

The company operates in the healthcare and biotechnology market, primarily serving patients who have undergone stem cell transplantation. Actitrexx's business model revolves around the production and clinical application of Actileucel. The product is classified as an Advanced Therapy Medicinal Product (ATMP), which means it is a highly specialized treatment produced through an automated process within 24 hours, making it ready for immediate clinical use.

Actitrexx generates revenue by providing this innovative treatment to healthcare providers and hospitals that perform stem cell transplants. The company aims to offer a curative therapy with minimal side effects, thereby improving the quality of life for patients suffering from GvHD.

In summary, Actitrexx is a biotech startup focused on developing advanced cellular therapies to treat GvHD, serving the healthcare market with a unique product that offers significant clinical benefits.

Keywords: Actileucel, GvHD, stem cell transplantation, regulatory T cells, cellular therapy, biotechnology, healthcare, ATMP, immune modulation, curative therapy.